Three-Layer Integration

Layer 1: Data Infrastructure

Unified data pipelines connecting genomic, proteomic, and phenotypic information with real-time experimental outputs from organ-on-chip and organoid systems.

Layer 2: Computational Models

AI-powered digital twins that integrate biological data to predict individual patient responses to therapeutic interventions.

Layer 3: Physical Systems

Microphysiological systems, organoids, and tissue chips that validate computational predictions with biological reality.

Platform Features

Multi-Organ Integration

Connect liver, kidney, heart, lung, and brain models for systemic drug response prediction.

Patient-Specific Modeling

iPSC-derived organoids enable personalized drug testing on patient-derived cells.

Real-Time Analytics

Continuous monitoring and analysis of biological responses across experimental timescales.

Regulatory Alignment

Data outputs designed for FDA Modernization Act compliance and regulatory submission.

A New Foundation for Human Simulation

A Patient Analog is the unified biological-computational representation of human physiology, integrating organoids, microphysiological systems, organ-on-chip platforms, multi-omics, and simulation engines into a single modeling substrate.

This hierarchy progresses from biological substrates to fully integrated, simulation-ready human models — establishing the foundational infrastructure that will define the next era of drug discovery and precision medicine.

The Human
Patient Analog
Digital Twin
System Analog
Organ Analog
Tissue / MPS
Organoid

The Human

The biological reality above all modeling frameworks

Patient Analog

Integrated bio-digital model of complete human

Digital Twin

Computational patient simulation platform

System Analog

Multi-organ physiological subsystems

Organ Analog

Individual organ modeled at high fidelity

Tissue / MPS

Engineered microphysiological systems

Organoid

3D cell cultures mimicking organ structure

FRAMEWORK ALIGNED WITH

NIH
NCATS
FDA
NAMs
ARPA-H
Health
DARPA
MPS
NASA
TissueChip
EMA
3Rs

Explore the Technology

Dive deeper into the core technologies powering the Patient Analog platform.

View Technologies